ESSENTIAL BINDING OF LUKF OF STAPHYLOCOCCAL GAMMA-HEMOLYSIN FOLLOWED BY THE BINDING OF H-GAMMA-II FOR THE HEMOLYSIS OF HUMAN ERYTHROCYTES

被引：31

作者：

OZAWA, T ^{[1
]}

KANEKO, J ^{[1
]}

KAMIO, Y ^{[1
]}

机构：

[1] TOHOKU UNIV, FAC AGR, DEPT APPL BIOL SCI, AOBA KU, SENDAI, MIYAGI 981, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1995年 / 59卷 / 06期

关键词：

D O I：

10.1271/bbb.59.1181

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Staphylococcal gamma-hemolysin consists of two protein components, LnkF and H gamma II. This report clarifies the order of binding of the two components to human erythrocytes for the hemolytic activity of the toxin. The initial binding of LukF to the human erythrocytes is essential for the subsequent binding of H gamma II to the same cells, with the formation of a heat-undissociable protein of about 100 kDa containing LukF and H gamma II.

引用

页码：1181 / 1183

页数：3

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