SERUM LONG-CHAIN ALCOHOL LEVELS IN HEALTHY-INDIVIDUALS AND IN PATIENTS WITH BREAST-CANCER

被引:2
作者
GILBERTSON, JR [1 ]
GELMAN, RA [1 ]
CHOBY, MA [1 ]
ZULLO, TG [1 ]
SARTIANO, GP [1 ]
机构
[1] UNIV PITTSBURGH, SCH MED, PITTSBURGH, PA 15261 USA
关键词
Blood serum; Breast cancer; Gas-liquid chromatography; Long-chain alcohols; Thin-layer chromatography;
D O I
10.1159/000225367
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Total long-chain alcohols were analyzed in blood sera from normal individuals and patients with diagnosed breast cancer. Tetra-, hexa- and octadecan-1-ol were the major long-chain alcohols detected in both groups. While the qualitative composition of the serum alcohols was similar in the 2 groups the average alcohol content of the serum of the breast cancer patients was approximately 6 .times. greater than that of the normal group. This difference in serum alcohol levels between the 2 groups was significant P < 0.01. [The possibility of using alcohol levels to diagnose breast cancer patients was discussed.].
引用
收藏
页码:144 / 147
页数:4
相关论文
共 12 条
[1]   ALKYL AND ALK-1-ENYL GLYCEROLS IN LIVER OF RATS FED LONG-CHAIN ALCOHOLS OR ALKYL GLYCEROLS [J].
BANDI, ZL ;
MANGOLD, HK ;
HOLMER, G ;
AAESJORG.E .
FEBS LETTERS, 1971, 12 (04) :217-+
[2]   METABOLISM OF UNUSUAL LIPIDS IN RAT .1. FORMATION OF UNSATURATED ALKYL AND ALK-I-ENYL CHAINS FROM ORALLY ADMINISTERED ALCOHOLS [J].
BANDI, ZL ;
AAESJORG.E ;
MANGOLD, HK .
BIOCHIMICA ET BIOPHYSICA ACTA, 1971, 239 (03) :357-+
[3]  
BLANK ML, 1972, LIPIDS, V5, P337
[4]  
EDWARDS AL, 1960, EXPT DESIGN PSYCHOLO
[5]  
FOLCH J, 1957, J BIOL CHEM, V226, P497
[6]  
GELMAN RA, 1975, NUTR METAB, V18, P169
[7]  
GILBERTSON JR, 1963, J BIOL CHEM, V238, P893
[9]   CHARACTERIZATION AND METABOLISM OF FREE FATTY ALCOHOLS FROM ESCHERICHIA-COLI [J].
NACCARATO, WF ;
GELMAN, RA ;
GILBERTSON, JR ;
KAWALEK, JC .
LIPIDS, 1972, 7 (05) :275-+
[10]  
SNYDER F, 1969, CANCER RES, V29, P251