PLASMA-LEVELS OF CEA AS A PROGNOSTIC MARKER IN CARCINOMA OF URINARY-BLADDER

被引：6

作者：

ALSABTI, EAK ^{[1
]}

SAFFO, MH ^{[1
]}

机构：

[1] ALBAATH SPECIF PROT REFERENCE UNIT,BAGHDAD,IRAQ

来源：

UROLOGIA INTERNATIONALIS | 1979年 / 34卷 / 05期

关键词：

Bladder carcinoma; Carcinoembryonic antigen; Prognosis;

D O I：

10.1159/000280285

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Plasma carcinoembryonic antigen (CEA) levels were performed pre-operatively by radioimmunoassay in 124 patients with histologically proved bladder carcinoma. The level of CEA was used to determine its prognostic value in patients with bladder cancer. The correlation of CEA levels with the stage of the disease, histology, and resectability was also studied. Values above 2.5 ng/ml were taken as abnormal. Active disease was associated with high CEA levels. All patients with CEA levels greater than 10 ng/ml died in less than l½ years, while all patients who survived l½–3 years had preoperative CEA levels less than 10 ng/ml. There was a prognostic significance for patients with transitional cell or squamous cell carcinoma. All patients with squamous cell carcinoma had CEA levels ≤10 ng/ml, and all patients with transitional carcinoma had preoperative CEA values > 10 ng/ml. A correlation between CEA levels and resectability of the primary tumor was found. This study indicates that, in bladder carcinoma patients, preoperative CEA levels greater than 10 ng/ml are of prognostic value, since all of these patients have died and all of the long-term survivors had levels ≤ 10 ng/ml. © 1979 S. Karger AG, Basel.

引用

页码：387 / 392

页数：6

共 17 条

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