ASSIGNMENT OF A HUMAN SERUM GLYCOPROTEIN-SP-40,40 GENE (CLI) TO CHROMOSOME-8

被引：22

作者：

TOBE, T ^{[1
]}

MINOSHIMA, S ^{[1
]}

YAMASE, S ^{[1
]}

CHOI, NH ^{[1
]}

TOMITA, M ^{[1
]}

SHIMIZU, N ^{[1
]}

机构：

[1] KEIO UNIV,SCH MED,DEPT MOLEC BIOL,TOKYO 108,JAPAN

来源：

CYTOGENETICS AND CELL GENETICS | 1991年 / 57卷 / 04期

关键词：

D O I：

10.1159/000133144

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

SP-40,40 is a serum glycoprotein consisting of two different subunits (alpha and beta) assembled into a dimer by disulfide bonds. Northern blot hybridization, using total RNA from several cell lines, showed that SP-40,40 is expressed in glioblastoma and testicular tumor cells, as well as hepatoma cells. Spot blot hybridization of flow-sorted human chromosomes, using a SP-40,40 cDNA fragment as a probe, localized the gene for SP-40,40 to human chromosome 8. This gene has been given the designation CLI, for complement lysis inhibitor, by the Human Gene Nomenclature Committee.

引用

页码：193 / 195

页数：3

共 17 条

[1] CHOI NH, 1989, MOL IMMUNOL, V26, P835
[2] CD59, AN LY-6-LIKE PROTEIN EXPRESSED IN HUMAN LYMPHOID-CELLS, REGULATES THE ACTION OF THE COMPLEMENT MEMBRANE ATTACK COMPLEX ON HOMOLOGOUS CELLS
DAVIES, A
SIMMONS, DL
HALE, G
HARRISON, RA
TIGHE, H
LACHMANN, PJ
WALDMANN, H
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1989, 170 (03) : 637 - 654
[3] DUIGUID JR, 1989, P NATL ACAD SCI USA, V86, P7260
[4] FEINBERG AP, 1983, ANAL BIOCHEM, V137, P226
[5] GENE FOR HUMAN CD59 (LIKELY LY-6 HOMOLOG) IS LOCATED ON THE SHORT ARM OF CHROMOSOME-11
FORSBERG, UH
BAZIL, V
STEFANOVA, I
SCHRODER, J
[J]. IMMUNOGENETICS, 1989, 30 (03) : 188 - 193
[6] MOLECULAR-STRUCTURE AND FUNCTIONAL-CHARACTERIZATION OF A HUMAN-COMPLEMENT CYTOLYSIS INHIBITOR FOUND IN BLOOD AND SEMINAL PLASMA - IDENTITY TO SULFATED GLYCOPROTEIN-2, A CONSTITUENT OF RAT TESTIS FLUID
JENNE, DE
TSCHOPP, J
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (18) : 7123 - 7127
[7] MOLECULAR-CLONING AND CHARACTERIZATION OF THE NOVEL, HUMAN COMPLEMENT-ASSOCIATED PROTEIN, SP-40,40 - A LINK BETWEEN THE COMPLEMENT AND REPRODUCTIVE SYSTEMS
KIRSZBAUM, L
SHARPE, JA
MURPHY, B
DAPICE, AJF
CLASSON, B
HUDSON, P
WALKER, ID
[J]. EMBO JOURNAL, 1989, 8 (03) : 711 - 718
[8] ASSIGNMENT OF THE MYELOPEROXIDASE GENE MPO TO HUMAN CHROMOSOME-17 USING SOMATIC-CELL HYBRIDS AND FLOW-SORTED CHROMOSOMES
KUDOH, J
MINOSHIMA, S
HASHINAKA, K
NISHIO, C
YAMADA, M
SHIMIZU, Y
SHIMIZU, N
[J]. JAPANESE JOURNAL OF HUMAN GENETICS, 1988, 33 (03): : 315 - 324
[9] MANIATIS T, 1982, MOL CLONING
[10] MICHEL D, 1989, ONCOGENE RES, V4, P127

← 1 2 →