NEUROPHARMACOLOGY OF 5-HYDROXYTRYPTAMINE(1B/D) RECEPTOR LIGANDS

被引:82
作者
CHOPIN, P [1 ]
MORET, C [1 ]
BRILEY, M [1 ]
机构
[1] CTR RECH PIERRE FABRE, DIV NEUROBIOL 1, F-81100 CASTRES, FRANCE
关键词
5-HT1B/D RECEPTOR SUBTYPES; BEHAVIOR; IN VIVO MICRODIALYSIS;
D O I
10.1016/0163-7258(94)90051-5
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
In spite of a lack of compounds acting selectively at the 5-hydroxytryptamine (5-HT)(1B) and 5-HT1D receptor subtypes, by cross-relating the available data, this review attempts to tentatively assign behavioural and other in vivo correlates of these receptor subtypes. In addition, a summary of data from microdialysis studies is included to develop an integrated view. Finally, a suggestion is made as to the possible pathophysiological consequences of 5-HT1D receptor dysfunction in man.
引用
收藏
页码:385 / 405
页数:21
相关论文
共 178 条