ZIPEPROL IS A NEWLY ABUSED ANTITUSSIVE WITH AN OPIOID SPECTRUM AND HALLUCINOGENIC EFFECTS

被引：7

作者：

JANIRI, L

MANNELLI, P

PERSICO, AM

DIODATO, S

TEMPESTA, E

机构：

[1] UNIV CATTOLICA SACRO CUORE, FAC MED, DEPT PSYCHIAT, DRUG ADDICT UNIT, I-00168 ROME, ITALY

[2] UNIV CATTOLICA SACRO CUORE, FAC MED, DEPT PHARMACOL, I-00168 ROME, ITALY

来源：

DRUG AND ALCOHOL DEPENDENCE | 1991年 / 27卷 / 02期

关键词：

ZIPEPROL; ANTITUSSIVE; DEPENDENCE; WITHDRAWAL;

D O I：

10.1016/0376-8716(91)90030-3

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Zipeprol is a non-opioid cough suppressor agent recently abused in Italy. Clinical reports from 30 street abusers show that the drug in high doses has a definite abuse liability and dependence potential. Many of its effects were identical to those induced by opiates, although specific dysperceptive symptoms were commonly reported by patients. Spontaneous withdrawal symptoms were similar to those of opiates. Withdrawal could be also precipitated by naloxone. It is concluded that zipeprol can induce dependence with a mechanism which may be mediated by some types of opioid receptors.

引用

页码：121 / 125

页数：5

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