RESULTS OF IVF FROM A PROSPECTIVE MULTICENTER STUDY

被引:40
作者
HAAN, G [1 ]
BERNARDUS, RE [1 ]
HOLLANDERS, JMG [1 ]
LEERENTVELD, RA [1 ]
PRAK, FM [1 ]
NAAKTGEBOREN, N [1 ]
机构
[1] STATE UNIV LIMBURG,INST MED TECHNOL ASSESSMENT,6200 MD MAASTRICHT,NETHERLANDS
关键词
INFERTILITY; IVF; PREGNANCY RATES; PROGNOSTIC FACTORS; MULTIVARIATE ANALYSIS;
D O I
10.1093/oxfordjournals.humrep.a137432
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Part of a cost-effectiveness study of in-vitro fertilization was the evaluation of the medical results of this fertility treatment. Data were prospectively collected from > 3000 IVF treatments in five Dutch hospitals during a 2-year period. The average 'take-at-least-one-healthy-baby-home-rate' per started treatment was 10% (the average clinical pregnancy rate per embryo transfer was 20%). After more IVF treatments, about one in three to four couples were successful. Differences in results were mainly caused by patient characteristics, the treatment episode and the treating hospital. These differences remained in a multivariate logistic regression analysis.
引用
收藏
页码:805 / 810
页数:6
相关论文
共 13 条
  • [1] De Mouzon J., French experience and results of a national collaborative prospective data recording system on IVF-ET, Fifth World Congress on in Vitro Fertilization and Embryo Transfer, Norfolk, VA, (1987)
  • [2] Engelman L., Stepwise logistic regression, BMDP Statistical Software. University of California Press, Berkeley, (1985)
  • [3] Guzick D., Wilkes C., Jones H., Cumulative pregnancy rates for in vitro fertilisation. Fertil, Steril, 46, pp. 663-667, (1986)
  • [4] Haan G., Effects and Costs of In-Vitro Fertilisation, (1989)
  • [5] Haan G., Bemardus R.E., Hollanders J.M.G., Leerentveld R.A., Prak F.M., Waegemaekers C.T.B.J., De resultaten van in vitro fertilisatie in een Nederlands multicentrisch onderzoek. Ned. Tijdsch, Geneesk, 134, pp. 2093-2098, (1990)
  • [6] Haan G., Bemardus R.E., Hollanders J.M.G., Leerentveld R.A., Prak F.M., Naaktgeboren N., Selective drop-out in successive IVF attempts: The pendulum danger, Hum. Reprod, (1991)
  • [7] Jones H., Acosta A., Rews M., Garcia J., Jones G., Mantzavinos T., McDowell J., Sandow B., Veeck L., Whibley T., Wilkes C., Wright G., What is a pregnancy? A question for programs of in vitro fertilization, Fertil. Steril, 40, (1983)
  • [8] Kleinbaum D., Kupper L., Morgenstern H., Epidemiologic Research, Principles and Quantitative Methods, (1982)
  • [9] Kloosterman G., De voortplanting van de mens. Leerboek voor obstet tie en gynaecologie, Centen Haarlem, (1977)
  • [10] In vitro feritlization/embryo transfer in the United States 1987 results from the National IVF/ET Registry, Fertil. Steril, 51, pp. 13-18, (1989)