SYNTHESIS OF POTENTIAL INHIBITORS OF SQUALENE EPOXIDASE

被引：8

作者：

MANN, J

SMITH, GP

机构：

[1] Department of Chemistry, Reading University, Whiteknights

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 11期

关键词：

D O I：

10.1039/p19910002884

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Squalene was degraded to tris-norsqualene aldehyde, and this was converted into 2-fluoromethyl-, 2,2-difluoromethyl-, 2-trimethylsilylmethyl-analogues of squalene, and into 2-cyano-norsqualene.

引用

页码：2884 / 2885

页数：2

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[8] TRISNORSQUALENE CYCLOPROPYLAMINE - A REVERSIBLE, TIGHT-BINDING INHIBITOR OF SQUALENE EPOXIDASE [J].

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