NOCTURNAL SLEEP IN HUNTINGTONS-DISEASE

被引：108

作者：

WIEGAND, M

MOLLER, AA

LAUER, CJ

STOLZ, S

SCHREIBER, W

DOSE, M

KRIEG, JC

机构：

[1] MAX PLANCK INST PSYCHIAT,W-8000 MUNICH,GERMANY

[2] UNIV FREIBURG,PSYCHIAT KLIN,W-7800 FREIBURG,GERMANY

[3] BEZIRKSKRANKENHAUS,W-8800 ANSBACH,GERMANY

来源：

JOURNAL OF NEUROLOGY | 1991年 / 238卷 / 04期

关键词：

HUNTINGTONS DISEASE; SLEEP EEG; BASAL GANGLIA DISORDERS;

D O I：

10.1007/BF00314781

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Nocturnal sleep was studied in 16 inpatients with Huntington's disease. In comparison with healthy controls, patients exhibited a disturbed sleep pattern with increased sleep onset latency, reduced sleep efficiency, frequent nocturnal awakenings, more time spent awake and less slow wave sleep. These abnormalities correlated in part with duration of illness, severity of clinical symptoms, and degree of atrophy of the caudate nucleus. Patients showed an increased density of sleep spindles.

引用

页码：203 / 208

页数：6

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