INITIATION OF TRANSCRIPTION BY RNA-POLYMERASE-II - A MULTISTEP PROCESS

被引：330

作者：

ZAWEL, L ^{[1
]}

REINBERG, D ^{[1
]}

机构：

[1] UNIV MED & DENT NEW JERSEY, ROBERT WOOD JOHNSON MED SCH, DEPT BIOCHEM, PISCATAWAY, NJ 08854 USA

来源：

PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 44 | 1993年 / 44卷

关键词：

D O I：

10.1016/S0079-6603(08)60217-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This chapter discusses the initiation of transcription of protein-coding genes. The RNA polymerase II(RNAPII) of the yeast Saccharomyces cerevisiae has been a useful prototype in the study of eukaryotic RNAPII, as features such as function and subunit structure have been highly conserved. The yeast RNAPII is composed of 11 polypeptides with apparent masses ranging from 220 to 10 kDa. This is in contrast to eukaryotic cells, which contain three distinct RNA polymerases, each containing from 8 to 14 polypeptides and responsible for transcribing its own set of genes: RNA polymerase I (RNAPI), which transcribes ribosomal RNA; RNAPII, the RNA polymerase of protein-coding, or class 11, genes; and RNAPIII, which transcribes 5-S rRNA and tRNA genes. In this chapter, only RNAPII is discussed, and only as it pertains to transcription initiation. © 1993 Academic Press Inc.

引用

页码：67 / 108

页数：42

共 142 条

[1] THE C-TERMINAL DOMAIN OF THE LARGEST SUBUNIT OF RNA POLYMERASE-II OF SACCHAROMYCES-CEREVISIAE, DROSOPHILA-MELANOGASTER, AND MAMMALS - A CONSERVED STRUCTURE WITH AN ESSENTIAL FUNCTION [J].

ALLISON, LA ;

WONG, JKC ;

FITZPATRICK, VD ;

MOYLE, M ;

INGLES, CJ .

MOLECULAR AND CELLULAR BIOLOGY, 1988, 8 (01) :321-329

[2] MUTATIONS IN RNA POLYMERASE-II ENHANCE OR SUPPRESS MUTATIONS IN GAL4 [J].

ALLISON, LA ;

INGLES, CJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (08) :2794-2798

[3] EXTENSIVE HOMOLOGY AMONG THE LARGEST SUBUNITS OF EUKARYOTIC AND PROKARYOTIC RNA-POLYMERASES [J].

ALLISON, LA ;

MOYLE, M ;

SHALES, M ;

INGLES, CJ .

CELL, 1985, 42 (02) :599-610

[4]

ARIAS JA, 1991, J BIOL CHEM, V266, P8055

[5] CHARACTERIZATION OF CDNA FOR THE LARGE SUBUNIT OF THE TRANSCRIPTION INITIATION-FACTOR TFIIF [J].

ASO, T ;

VASAVADA, HA ;

KAWAGUCHI, T ;

GERMINO, FJ ;

GANGULY, S ;

KITAJIMA, S ;

WEISSMAN, SM ;

YASUKOCHI, Y .

NATURE, 1992, 355 (6359) :461-464

[6] ACTIVATION OF DNA-BINDING ACTIVITY IN AN APPARENTLY CYTOPLASMIC PRECURSOR OF THE NF-KAPPA-B TRANSCRIPTION FACTOR [J].

BAEUERLE, PA ;

BALTIMORE, D .

CELL, 1988, 53 (02) :211-217

[7] GENETIC-ANALYSIS OF THE REPETITIVE CARBOXYL-TERMINAL DOMAIN OF THE LARGEST SUBUNIT OF MOUSE RNA POLYMERASE-II [J].

BARTOLOMEI, MS ;

HALDEN, NF ;

CULLEN, CR ;

CORDEN, JL .

MOLECULAR AND CELLULAR BIOLOGY, 1988, 8 (01) :330-339

[8] INITIATION OF TRANSCRIPTION OF THE ERYTHROID PROMOTER OF THE PORPHOBILINOGEN DEAMINASE GENE IS REGULATED BY A CIS-ACTING SEQUENCE AROUND THE CAP SITE [J].

BEAUPAIN, D ;

ELEOUET, JF ;

ROMEO, PH .

NUCLEIC ACIDS RESEARCH, 1990, 18 (22) :6509-6515

[9] THE PROTEIN ID - A NEGATIVE REGULATOR OF HELIX-LOOP-HELIX DNA-BINDING PROTEINS [J].

BENEZRA, R ;

DAVIS, RL ;

LOCKSHON, D ;

TURNER, DL ;

WEINTRAUB, H .

CELL, 1990, 61 (01) :49-59

[10] ROLE OF THE MAMMALIAN TRANSCRIPTION FACTOR-IIF, FACTOR-IIS, AND FACTOR-IIX DURING ELONGATION BY RNA POLYMERASE-II [J].

BENGAL, E ;

FLORES, O ;

KRAUSKOPF, A ;

REINBERG, D ;

ALONI, Y .

MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (03) :1195-1206

← 1 2 3 4 5 6 7 8 9 10 →