INDUCTION OF CHROMOSOMAL BREAKAGE IN CULTURED HUMAN LEUCOCYTES BY LUTEOSKYRIN

被引：6

作者：

KEUTEL, J

MOCKEL, H

机构：

[1] Department of Human Genetics, University of Marburg a. d. L., Marburg

来源：

HUMANGENETIK | 1969年 / 7卷 / 04期

关键词：

D O I：

10.1007/BF00283556

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Luteoskyrin, a Polyhydroxy-Bis-Dihydroanthrachinon isolated from Penicillium islandicum Sopp, is known to have strong cytotoxic effects. In long-term cultures of Ehrilich-Ascites-Tumour cells it causes the formation of very long abnormal chromosomes (Schachtschabel). Experiments with short-term cultures of human leucocytes are reported on which have shown Luteoskyrin to induce chromosomal breaks and interchromosomal bridges. © 1969 Springer-Verlag.

引用

页码：344 / &

共 13 条

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