A ROLE FOR THE AUTONOMIC NERVOUS-SYSTEM IN MODULATING THE IMMUNE-RESPONSE DURING MILD EMOTIONAL STIMULI

被引：30

作者：

CROISET, G

HEIJNEN, CJ

VANDERWAL, WE

DEBOER, SF

DEWIED, D

机构：

[1] STATE UNIV UTRECHT,HET WILHELMINA KINDERZIEKENHUIS,DEPT PEDIAT IMMUNOL,UTRECHT,NETHERLANDS

[2] FAC PHARM UTRECHT,NETHERLANDS INST DRUGS & DOPING RES,UTRECHT,NETHERLANDS

来源：

LIFE SCIENCES | 1990年 / 46卷 / 06期

关键词：

D O I：

10.1016/0024-3205(90)90085-6

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The role of the autonomic nervous system in the modulation of the immune response to emotional stimuli, was established in rats subjected to the passive avoidance test. An increase in splenic primary antibody response directed against SRBC was found after exposure of rats to the passive avoidance apparatus (novelty). Both local surgical denervation of the spleen and β-receptor blockade (timolol, 1 mg/kg i.p. 1 h prior to testing) prevented the increase in primary antibody response. © 1990.

引用

页码：419 / 425

页数：7

共 26 条

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