A FACILE SYNTHESIS OF 4-HYDROXY-2(E)-NONENAL

被引：60

作者：

GARDNER, HW

BARTELT, RJ

WEISLEDER, D

机构：

[1] National Center for Agricultural Utilization Research, Agricultural Research Service, USDA, Peoria, 61604, Illinois

来源：

LIPIDS | 1992年 / 27卷 / 09期

关键词：

D O I：

10.1007/BF02536025

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A facile, efficient synthesis of 4-hydroxy-2(E)-nonenal is presented as an alternative to the approaches published previously, which either employed four to six separate steps or furnished low yields. The commercially available 3(Z)-nonenol was sequentially oxidized into 3,4-epoxynonanol by 3-chloroperoxybenzoic acid followed by oxidation of the alcohol by periodinane to afford 4-hydroxy-2(E)-nonenal by this two-step procedure in 48 +/- 7% yield.

引用

页码：686 / 689

页数：4

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