2 KININS ISOLATED FROM AN EXTRACT OF THE VENOM RESERVOIRS OF THE SOLITARY WASP MEGASCOLIA-FLAVIFRONS

被引：44

作者：

YASUHARA, T

MANTEL, P

NAKAJIMA, T

PIEK, T

机构：

[1] UNIV AMSTERDAM, DEPT PHARMACOL, 1105 AZ AMSTERDAM, NETHERLANDS

[2] UNIV TOKYO, FAC PHARMACEUT SCI, BUNKYO KU, TOKYO 113, JAPAN

来源：

TOXICON | 1987年 / 25卷 / 05期

关键词：

D O I：

10.1016/0041-0101(87)90288-1

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

From an exact of the venom reservoirs of the wasp Megascolia flavifrons two kinins have been isolated. The sequences of amino acids are: Arg-Pro-Pro-Gly-Phe-Thr-Pro-Phe-Arg (Thr6-bradykinin) and Arg-Pro-Pro-Gly-Phe-Thr-Pro-Phe-Arg-Lys-Ala (Thr6-bradykinin-Lys-Ala). The bradykinin-like effects of the venom on a numberof vertebrate smooth muscle preparations can be explained by the actions of these kinins.

引用

页码：527 / 535

页数：9

共 16 条

[1]

[Anonymous], 1970, PHARM EXPT ISOLATED

[2] NEW PLASMA KININ IN TURTLE, PSEUDEMYS-SCRIPTA-ELEGANS [J].

DUNN, RS ;

PERKS, AM .

EXPERIENTIA, 1970, 26 (11) :1220-&

[3]

Fabre J.H., 1879, SOUVENIRS ENTOMOLOGI

[4] DISAPPEARANCE OF BRADYKININ AND ELEDOISIN IN CIRCULATION AND VASCULAR BEDS OF CAT [J].

FERREIRA, SH ;

VANE, JR .

BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1967, 30 (02) :417-&

[5] FURTHER-STUDIES OF MYOMETRIAL BRADYKININ RECEPTOR-LIKE BINDING [J].

FREDRICK, MJ ;

VAVREK, RJ ;

STEWART, JM ;

ODYA, CE .

BIOCHEMICAL PHARMACOLOGY, 1984, 33 (18) :2887-2892

[6]

Nakajima T., 1986, P309

[7]

PASSERINI C, 1840, LETTE PISA ALLA SEZI

[8]

PASSERINI C, 1841, LETTE FIRENZE ALLA S

[9] MEGASCOLIAKININ, A BRADYKININ-LIKE COMPOUND IN THE VENOM OF MEGASCOLIA-FLAVIFRONS FAB (HYMENOPTERA, SCOLIIDAE) [J].

PIEK, T ;

MANTEL, P ;

VANGINKEL, CJW .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY, 1984, 78 (02) :473-474

[10] SMOOTH-MUSCLE CONTRACTING COMPOUNDS IN THE VENOM OF MEGASCOLIA-FLAVIFRONS (HYM, SCOLIIDAE) WITH NOTES ON THE STINGING BEHAVIOR [J].

PIEK, T ;

BUITENHUIS, A ;

SIMONTHOMAS, RT ;

UFKES, JGR ;

MANTEL, P .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY, 1983, 75 (01) :145-152

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