POTENTIAL THERAPEUTIC EXPLOITATION OF THE PULMONARY POLYAMINE UPTAKE SYSTEM

被引：5

作者：

COHEN, GM ^{[1
]}

SMITH, LL ^{[1
]}

机构：

[1] ICI PLC,CENT TOXICOL LAB,BIOCHEM TOXICOL SECT,MACCLESFIELD SK10 4TG,CHESHIRE,ENGLAND

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 1990年 / 18卷 / 05期

关键词：

D O I：

10.1042/bst0180743

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：743 / 745

页数：3

共 28 条

[1] POLYAMINE METABOLISM - A POTENTIAL THERAPEUTIC TARGET IN TRYPANOSOMES [J].

BACCHI, CJ ;

NATHAN, HC ;

HUTNER, SH .

SCIENCE, 1980, 210 (4467) :332-334

[2] NOVEL COMBINATION CHEMOTHERAPY OF EXPERIMENTAL TRYPANOSOMIASIS BY USING BLEOMYCIN AND DL-ALPHA-DIFLUOROMETHYLORNITHINE - REVERSAL BY POLYAMINES [J].

BACCHI, CJ ;

NATHAN, HC ;

HUTNER, SH ;

MCCANN, PP ;

SJOERDSMA, A .

BIOCHEMICAL PHARMACOLOGY, 1982, 31 (17) :2833-2836

[3] EFFICACY OF COMBINATIONS OF DIFLUOROMETHYLORNITHINE AND BLEOMYCIN IN A MOUSE MODEL OF CENTRAL NERVOUS-SYSTEM AFRICAN TRYPANOSOMIASIS [J].

CLARKSON, AB ;

BACCHI, CJ ;

MELLOW, GH ;

NATHAN, HC ;

MCCANN, PP ;

SJOERDSMA, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (18) :5729-5733

[4]

CULLIS P M, 1990, Medical Science Research, V18, P87

[5] THE VALUE OF INFUSION AND INJECTION REGIMENS IN ASSESSING EFFICACY AND TOXICITY OF DRUGS [J].

FARA, J ;

URQUHART, J .

TRENDS IN PHARMACOLOGICAL SCIENCES, 1984, 5 (01) :21-25

[6]

FIELD M, 1964, CANCER RES, V24, P1939

[7] PULMONARY ACCUMULATION OF METHYLGLYOXAL-BIS(GUANYLHYDRAZONE) BY THE OLIGOAMINE UPTAKE SYSTEM [J].

GORDONSMITH, RH ;

SMITH, LL ;

COHEN, GM .

BIOCHEMICAL PHARMACOLOGY, 1985, 34 (10) :1809-1816

[8] STRUCTURAL REQUIREMENTS OF COMPOUNDS TO INHIBIT PULMONARY DIAMINE ACCUMULATION [J].

GORDONSMITH, RH ;

BROOKETAYLOR, S ;

SMITH, LL ;

COHEN, GM .

BIOCHEMICAL PHARMACOLOGY, 1983, 32 (24) :3701-3709

[9]

GORDONSMITH RH, 1985, THESIS LONDON U

[10]

HESTON WDW, 1984, CANCER RES, V44, P1034

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