PARENTAL HLA SHARING, FETOMATERNAL COMPATIBILITY AND NEONATAL BIRTH-WEIGHT IN FAMILIES WITH A HISTORY OF RECURRENT SPONTANEOUS-ABORTION

被引：5

作者：

KILPATRICK, DC

LISTON, WA

机构：

[1] ROYAL EDINBURGH & ASSOCIATED HOSP, DEPT TRANSFUS MED, EDINBURGH EH3 9HB, MIDLOTHIAN, SCOTLAND

[2] ROYAL EDINBURGH & ASSOCIATED HOSP, DEPT OBSTET & GYNECOL, EDINBURGH EH3 9HB, MIDLOTHIAN, SCOTLAND

来源：

DISEASE MARKERS | 1993年 / 11卷 / 2-3期

关键词：

MHC; RECURRENT MISCARRIAGE; ANTIGEN SHARING;

D O I：

10.1155/1993/174382

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The mean birthweight of babies eventually born to couples with a history of recurrent spontaneous abortion (RSA) is allegedly lower if the parents have a high degree of HLA antigen sharing (Reznikoff-Etievant et al., 1991), but this relationship has not been independently confirmed. We have re-investigated this question by analysing data from 36 families. In 22 instances, we were able to relate birthweight directly to feto-maternal HLA compatibility for the first time in such families. We were unable to confirm any appreciable influence of paternal or feto-maternal HLA sharing on birthweight or placental weight and conclude that RSA families do not differ markedly from normal families in this respect.

引用

页码：125 / 130

页数：6

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