CHEMORADIOPROTECTION OF THE RAT PAROTID-GLAND BY COMBINED USE OF WR-2721 AND RO-07-0582

被引:16
作者
SODICOFF, M [1 ]
CONGER, AD [1 ]
PRATT, NE [1 ]
SINESI, M [1 ]
TREPPER, P [1 ]
机构
[1] TEMPLE UNIV,SCH MED,DEPT RADIOBIOL,PHILADELPHIA,PA 19140
关键词
D O I
10.2307/3575063
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The radioprotection of the rat parotid gland by WR-2721 alone (DMF, 2.4) was compared to the protection afforded when WR-2721 was given in combination with the hypoxic cell radiosensitizer Ro-07-0582 (DMF, 2.6). It was concluded that the radiosensitizer of malignant tumor cells Ro-07-0582 was compatible with and did not reduce the protection of normal tissue afforded by WR-2721.
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页码:348 / 353
页数:6
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