PROTEIN-STRUCTURE - BORN TO BE BETA

被引：22

作者：

REGAN, L

机构：

[1] Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511

来源：

CURRENT BIOLOGY | 1994年 / 4卷 / 07期

关键词：

D O I：

10.1016/S0960-9822(00)00147-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The beta-sheet-forming propensities of amino acids have been measured in a new model system. The origins of observed variations in the propensities are unclear, but the results provide a useful tool for protein design.

引用

页码：656 / 658

页数：3

共 15 条

[1] HYDROGEN-BOND STRENGTH AND BETA-SHEET PROPENSITIES - THE ROLE OF A SIDE-CHAIN BLOCKING EFFECT [J].

BAI, YW ;

ENGLANDER, SW .

PROTEINS-STRUCTURE FUNCTION AND GENETICS, 1994, 18 (03) :262-266

[2] PRIMARY STRUCTURE EFFECTS ON PEPTIDE GROUP HYDROGEN-EXCHANGE [J].

BAI, YW ;

MILNE, JS ;

MAYNE, L ;

ENGLANDER, SW .

PROTEINS-STRUCTURE FUNCTION AND GENETICS, 1993, 17 (01) :75-86

[3] STRUCTURAL BASIS OF AMINO-ACID ALPHA-HELIX PROPENSITY [J].

BLABER, M ;

ZHANG, XJ ;

MATTHEWS, BW .

SCIENCE, 1993, 260 (5114) :1637-1640

[4]

Chou P Y, 1978, Adv Enzymol Relat Areas Mol Biol, V47, P45

[5] SIDE-CHAIN ENTROPY OPPOSES ALPHA-HELIX FORMATION BUT RATIONALIZES EXPERIMENTALLY DETERMINED HELIX-FORMING PROPENSITIES [J].

CREAMER, TP ;

ROSE, GD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (13) :5937-5941

[6] A NOVEL, HIGHLY STABLE FOLD OF THE IMMUNOGLOBULIN BINDING DOMAIN OF STREPTOCOCCAL PROTEIN-G [J].

GRONENBORN, AM ;

FILPULA, DR ;

ESSIG, NZ ;

ACHARI, A ;

WHITLOW, M ;

WINGFIELD, PT ;

CLORE, GM .

SCIENCE, 1991, 253 (5020) :657-661

[7] DIFFERENTIAL HELIX PROPENSITY OF SMALL APOLAR SIDE-CHAINS STUDIED BY MOLECULAR-DYNAMICS SIMULATIONS [J].

HERMANS, J ;

ANDERSON, AG ;

YUN, RH .

BIOCHEMISTRY, 1992, 31 (24) :5646-5653

[8] ALPHA-HELIX STABILITY IN PROTEINS .2. FACTORS THAT INFLUENCE STABILITY AT AN INTERNAL POSITION [J].

HOROVITZ, A ;

MATTHEWS, JM ;

FERSHT, AR .

JOURNAL OF MOLECULAR BIOLOGY, 1992, 227 (02) :560-568

[9] PEPTIDOMIMETICS AND THE TEMPLATE APPROACH TO NUCLEATION OF BETA-SHEETS AND ALPHA-HELICES IN PEPTIDES [J].

KEMP, DS .

TRENDS IN BIOTECHNOLOGY, 1990, 8 (09) :249-255

[10] THERMODYNAMIC BETA-SHEET PROPENSITIES MEASURED USING A ZINC-FINGER HOST PEPTIDE [J].

KIM, CWA ;

BERG, JM .

NATURE, 1993, 362 (6417) :267-270

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