(2R,4S)-2-AMINOMETHYL-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID DIHYDROCHLORIDE - SYNTHESIS, EPIMERIZATION, AND DERIVATIVES

被引：5

作者：

IMMING, P

机构：

[1] Institut für Pharmazeutische Chemie, Marburg, D-35032

来源：

ARCHIV DER PHARMAZIE | 1995年 / 328卷 / 01期

关键词：

D O I：

10.1002/ardp.19953280115

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The preparation of the title compound 6a from penicillamine 5 or from penicillins 7, the spectroscopic data and stereochemical assignments are given. 6a quickly epimerizes at C-2 in dilute aqueous solution. Details are given along with the preparation of the new thiazolidines 10-13 from 6.

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页码：81 / 86

页数：6

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