MOLECULAR-CLONING AND SEQUENCE OF THE GENE FOR OUTER-MEMBRANE PROTEIN-P5 OF HAEMOPHILUS-INFLUENZAE

被引:42
作者
MUNSON, RS
GRASS, S
WEST, R
机构
[1] ST LOUIS CHILDRENS HOSP,DIV INFECT DIS,ST LOUIS,MO 63178
[2] WASHINGTON UNIV,SCH MED,DEPT MOLEC MICROBIOL,ST LOUIS,MO 63110
关键词
D O I
10.1128/IAI.61.9.4017-4020.1993
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The gene for outer membrane protein P5 of Haemophilus influenzae was identified by immunological screening of a genomic lambdaEMBL3 library of the serotype b strain 1613. The gene was subcloned, and plasmid clones expressing P5 were identified by immunologic screening. The gene for outer membrane protein P5 was sequenced. The mature protein has a molecular weight of 35,628. The protein is 50% identical and 65% similar to the OmpA protein of Escherichia coli.
引用
收藏
页码:4017 / 4020
页数:4
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