THE PARABRACHIO-SUBFORNICAL ORGAN PROJECTION IN THE RAT

被引:23
作者
GU, GB [1 ]
JU, G [1 ]
机构
[1] FOURTH MIL MED UNIV, INST NEUROSCI, XIAN 710032, PEOPLES R CHINA
基金
中国国家自然科学基金;
关键词
PARABRACHIAL NUCLEUS; SUBFORNICAL ORGAN; ANTEROGRADE TRACING; RETROGRADE TRACING; CARDIOVASCULAR CONTROL; DRINKING BEHAVIOR;
D O I
10.1016/0361-9230(95)00070-U
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Previous physiological studies have shown that both the parabrachial nucleus and the subfornical organ are involved in drinking behavior and cardiovascular controls. The purpose of the present work was to study the direct connections between these two structures by using anterograde and retrograde transport methods. A mixture of wheat germ agglutinin conjugated with horseradish peroxidase and free horseradish peroxidase or Fluorogold was injected into either the parabrachial nucleius (PBN) or the subfornical organ (SFO). The results indicated that the parabrachial nucleus sends a substantial projection to the entirety of the subfornical organ,and this input appears to be distributed to both the central and peripheral regions of this structure. Neurons that give origin to this projection are mainly located in the outer layer of the lateral division of the parabrachial nucleus, including the superior, internal, dorsal, and external lateral subnuclei. These findings suggest that, besides the already known connections, there is an additional parabrachio-subfornical pathway that may be involved in the central integration of cardiovascular function and drinking behavior.
引用
收藏
页码:41 / 47
页数:7
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