CORRELATION OF DNA DISTRIBUTION AND CYTOLOGICAL DIFFERENTIATION OF HUMAN CERVICAL CARCINOMAS

被引：16

作者：

JAKOBSEN, A ^{[1
]}

BICHEL, P ^{[1
]}

SELL, A ^{[1
]}

机构：

[1] RADIUM CTR,DK-8000 AARHUS C,DENMARK

来源：

VIRCHOWS ARCHIV B-CELL PATHOLOGY INCLUDING MOLECULAR PATHOLOGY | 1979年 / 31卷 / 01期

关键词：

Biopsy specimen; Cytological differentiation; Flow cytometry; Human cervix cancer;

D O I：

10.1007/BF02889925

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

The DNA distribution of biopsy specimens from 46 patients suffering from cervical carcinoma was analysed by flow cytometry and compared with the cytological differentiation. According to morphological criteria the carcinomas were classified as highly differentiated, moderately differentiated and poorly differentiated. The results demonstrate that highly differentiated tumours contain hyperploid cells predominantly with hyperdiploid DNA content. Hyperploid cell populations in the moderately differentiated tumours are mainly in the hyperdiploid and tetraploid regions. Poorly differentiated tumours contain hypertetraploid and aneuploid cell populations. The significance of these findings is discussed. © 1979 Springer-Verlag.

引用

页码：75 / 79

页数：5

共 11 条

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[2]

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[3]

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