TRANSFERRIN IS A GROWTH-FACTOR FOR THE BLOOD-STREAM FORM OF TRYPANOSOMA-BRUCEI

被引:70
作者
SCHELL, D [1 ]
BOROWY, NK [1 ]
OVERATH, P [1 ]
机构
[1] MAX PLANCK INST BIOL,MEMBRANBIOCHEM ABT,CORRENSSTR 38,W-7400 TUBINGEN,GERMANY
来源
PARASITOLOGY RESEARCH | 1991年 / 77卷 / 07期
关键词
D O I
10.1007/BF00931012
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
A method for the selective depletion of transferrin from bovine serum is presented. Bloodstream forms of Trypanosoma brucei cannot grow in medium containing transferrin-deficient serum, whereas reconstitution with transferrin restores normal growth. We conclude that transferrin is an essential growth factor for the mammalian stage of the parasite.
引用
收藏
页码:558 / 560
页数:3
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