IMPLICATION OF STEROID SAPONINS AND SAPOGENINS IN THE HYPOCHOLESTEROLEMIC EFFECT OF FENUGREEK

被引：139

作者：

SAUVAIRE, Y ^{[1
]}

RIBES, G ^{[1
]}

BACCOU, JC ^{[1
]}

LOUBATIERESMARIANI, MM ^{[1
]}

机构：

[1] FAC MED MONTPELLIER,INST BIOL,PHARMACOL LAB,CNRS,URA 599,F-34060 MONTPELLIER,FRANCE

来源：

LIPIDS | 1991年 / 26卷 / 03期

关键词：

D O I：

10.1007/BF02543970

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The transformation of fenugreek subfractions, rich in steroid saponins, was studied upon their passage through the digestive tract to determine the contribution of saponins and/or diosgenin and other steroid sapogenins to the hypocholesterolemic effect of fenugreek seeds. Feces of alloxan diabetic dogs fed fenugreek subfractions were analyzed, and diosgenin, smilagenin and gitogenin were identified and measured using capillary gas chromatography/mass spectrometry. Our results show that saponins are, in part (about 57%), hydrolyzed into sapogenins in the digestive tract. It appears that saponins may be implicated, alone or together with diosgenin, in the observed hypocholesterolemic effect of fenugreek seeds in diabetic dogs.

引用

页码：191 / 197

页数：7

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