PRIMARY LEIOMYOSARCOMA OF ADRENAL-GLAND - CASE-REPORT WITH IMMUNOHISTOCHEMICAL AND ULTRASTRUCTURAL-STUDY

被引：41

作者：

LACK, EE ^{[1
]}

GRAHAM, CW ^{[1
]}

AZUMI, N ^{[1
]}

BITTERMAN, P ^{[1
]}

RUSNOCK, EJ ^{[1
]}

OBRIEN, W ^{[1
]}

LYNCH, JH ^{[1
]}

机构：

[1] GEORGETOWN UNIV,SCH MED,DEPT UROL,WASHINGTON,DC 20007

来源：

AMERICAN JOURNAL OF SURGICAL PATHOLOGY | 1991年 / 15卷 / 09期

关键词：

ADRENAL; LEIOMYOSARCOMA; SMOOTH MUSCLE;

D O I：

10.1097/00000478-199109000-00011

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

A primary leiomyosarcoma of the right adrenal gland is reported in a 49-year-old male who presented with progressive flank pain. This is the second case in the English language literature and the first to have documentation of malignant behavior. The tumor measured 11 cm in diameter and showed marked necrosis with prominent mitotic activity (average 15 per 10 high-power fields). Smooth muscle differentiation was apparent ultrastructurally and confirmed by positive immunostaining for muscle-specific and alpha-smooth muscle actin. Bony metastases developed; following palliative treatment with radiation and chemotherapy, the patient is alive with tumor 9 months later. Origin from smooth muscle associated with the central adrenal vein or its tributaries is proposed.

引用

页码：899 / 905

页数：7

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