VISCOSITY SENSING WITH LAMB-WAVE MICROSENSOR - DIMETHYLSULFOXIDE SOLUTION VISCOSITY AS A FUNCTION OF TEMPERATURE

被引:14
作者
ETO, TK
COSTELLO, BJ
WENZEL, SW
WHITE, RM
RUBINSKY, B
机构
[1] UNIV CALIF BERKELEY,DEPT ELECT ENGN & COMP SCI,BERKELEY,CA 94720
[2] UNIV CALIF BERKELEY,UNIV CALIF SAN FRANCISCO,JOINT BIOENGN GRAD PROGRAM,BERKELEY,CA 94720
[3] UNIV CALIF BERKELEY,BERKELEY SENSOR & ACTUATOR CTR,BERKELEY,CA 94720
来源
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME | 1993年 / 115卷 / 03期
关键词
D O I
10.1115/1.2895494
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Recently, a new microsensor employing low-velocity ultrasonic Lamb waves was developed and demonstrated to be capable of measuring the viscosity of solutions in small volumes. The microsensor, when attached to a temperature-controlled stage, can measure viscosity as a function of temperature. In this investigation, the ultrasonic Lamb-wave oscillator is employed to experimentally measure the viscosity of dimethylsulfoxide (Me2SO) solutions as a function of temperature. The microsensor and the experimental procedure are described and results for 1M, 3M, and 5M Me2SO aqueous solutions are presented. Dimethylsulfoxide is a compound commonly employed as a cryoprotectant in cryopreservation, the low-temperature preservation of biological materials. The temperature dependence of viscosity obtained through this study can be used in determining the probability for ice nucleation in biological materials, a parameter of importance during cryopreservation.
引用
收藏
页码:329 / 331
页数:3
相关论文
共 14 条
[1]  
[Anonymous], 1967, RAYLEIGH LAMB WAVES
[2]  
FRIEDLER S, 1988, FERTIL STERIL, V49, P743
[3]   PHARMACOLOGY OF DMSO [J].
JACOB, SW ;
HERSCHLER, R .
CRYOBIOLOGY, 1986, 23 (01) :14-27
[4]   THE EFFECT ON FERTILIZATION OF EXPOSURE OF MOUSE OOCYTES TO DIMETHYL-SULFOXIDE - AN OPTIMAL PROTOCOL [J].
JOHNSON, MH .
JOURNAL OF IN VITRO FERTILIZATION AND EMBRYO TRANSFER, 1989, 6 (03) :168-175
[5]   CRYOPROTECTION BY DIMETHYLSULFOXIDE AND DIMETHYL SULFONE [J].
MCGANN, LE ;
WALTERSON, ML .
CRYOBIOLOGY, 1987, 24 (01) :11-16
[6]  
MOORE WJ, 1972, PHYSICAL CHEM, P924
[7]  
PEGG DE, 1986, CRYO-LETT, V7, P387
[8]   A CRYOMICROSCOPE USING DIRECTIONAL SOLIDIFICATION FOR THE CONTROLLED FREEZING OF BIOLOGICAL-MATERIAL [J].
RUBINSKY, B ;
IKEDA, M .
CRYOBIOLOGY, 1985, 22 (01) :55-68
[9]   THERMODYNAMICS AND KINETICS OF INTRACELLULAR ICE FORMATION DURING FREEZING OF BIOLOGICAL CELLS [J].
TONER, M ;
CRAVALHO, EG ;
KAREL, M .
JOURNAL OF APPLIED PHYSICS, 1990, 67 (03) :1582-1593
[10]   UNDER WHAT CONDITIONS CAN A GLASS BE FORMED [J].
TURNBULL, D .
CONTEMPORARY PHYSICS, 1969, 10 (05) :473-&