BIOSYNTHESIS OF N-METHYLPELLETIERINE

被引：24

作者：

GUPTA, RN

SPENSER, ID

机构：

[1] Department of Chemistry, McMaster University, Hamilton, Ont.

来源：

PHYTOCHEMISTRY | 1969年 / 8卷 / 10期

关键词：

D O I：

10.1016/S0031-9422(00)88080-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The biosynthesis of N-methylpelletierine (VII) was studied in excised shoots of Sedum sarmentosum. Consistent with classical biogenetic concepts, the piperidine nucleus of the alkaloid is generated from lysine, which is incorporated by way of nonsymmetrical intermediates, very probably ε{lunate}-amino-α-ketocaproic acid and Δ1-piperideine-2-carboxylic acid. The propanone side-chain originates from acetate. Direct incorporation into the side-chain of an intact three-carbon unit derived from acetoacetate could not be demonstrated. © 1970.

引用

页码：1937 / +

页数：1

共 48 条

[1] A SYNTHESIS OF ISO-PELLETIERINE AND METHYL ISO-PELLETIERINE [J].