STUDIES OF ISOMERIC COMPOSITION OF BILIVERDIN AND BILIRUBIN BY MASS SPECTROMETRY

被引：32

作者：

NICHOL, AW

MORELL, DB

机构：

[1] Institute of Medical Research, The Royal North Shore Hospital of Sydney, Crows Nest

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1969年 / 184卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0304-4165(69)90112-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The isomeric composition of bile pigments produced both in vivo and in vitro has been investigated using both mass and NMR spectrometry. Bile pigments from mammalian, avian and algal sources were all found to be of the IXα type although traces of other isomers were present in the pigments derived from the two former sources. Biliverdin produced by coupled oxidation of haemoglobin and ascorbic acid in the presence of oxygen is also of the IXα type. Biliverdin produced by coupled oxidation of pyridine protohaemochrome and either hydrazine or ascrobic acid by oxygen is of the type IXβ or IXδ. Spectroscopic data are given for this compound which resembles closely the bile pigment formed by guinea pig liver homogenate and pyridine protohaemochrome. © 1969.

引用

页码：173 / &

共 27 条

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