学术探索
学术期刊
新闻热点
数据分析
智能评审

AUTONOMIC MODULATION OF CELLULAR REPOLARIZATION AND OF THE ELECTROCARDIOGRAPHIC QT INTERVAL

被引：32
作者：
ROSEN, MR
JECK, CD
STEINBERG, SF
机构：
[1] Departments of Pharmacology and Pediatrics, Columbia University, New York, New York
来源：
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY | 1992年 / 3卷 / 05期
关键词：
REPOLARIZING CURRENTS; LONG QT SYNDROME; SYMPATHETIC AGONISTS AND BLOCKERS; MUSCARINIC AGONISTS AND BLOCKERS;
D O I：
10.1111/j.1540-8167.1992.tb00991.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Autonomic Modulation of Repolarization. The modulation of repolarization on ECG, the currents contributing to it in cardiac myocytes, and the effects of autonomic stimulation on repolarization are all complex areas that not only influence the normal rhythm of the heart, but have important implications with respect to arrhythmias. The following is a brief review that stresses the role of autonomic modulation of repolarization, summarizing the extent of our information with respect to the normal heart and the dysrhythmic heart. Particular emphasis is placed on the long QT syndrome and its relationship to lethal arrhythmias.
引用
收藏
页码：487 / 499
页数：13
相关论文
共 114 条
  • [1] Kulliker A, Muller H, Nachweis der negativen Schwankung des muskelstroms am naturlich sich contrahirenden muskel. Verhandlungen der physi‐kalisch‐medicinischen Gesellschaft i, Warzburg, 6, pp. 528-533, (1855)
  • [2] Burdon-Sanderson J, Page FMJ, On the time relations of the excitatory process in the ventricle of the frog, The Journal of Physiology, 2, pp. 384-435, (1880)
  • [3] Burdon-Sanderson J, Page FMJ, On the electrical phenomena of the excitatory process in the heart of the frog and of the tortoise, as investigated photographically, J Physiol, 4, pp. 327-338, (1883)
  • [4] Einthoven W, Uber die deutung des elektrokar‐diogramms, Pflügers Arch, 149, pp. 65-86, (1913)
  • [5] Mines GR, On functional analysis by the action of electrolytes, The Journal of Physiology, 46, pp. 188-235, (1913)
  • [6] Wilson FN, Macleod AG, Barker PS, The T deflection of the electrocardiogram, Trans Assoc Am Physicians, 46, pp. 29-38, (1931)
  • [7] Spach MS, Barr RC, Ventricular intramural and epicardial potential distributions during ventricular activation and repolarization in the intact dog, Circ Res, 37, pp. 243-257, (1975)
  • [8] Moore N, Preston JB, Moe GK, Durations of the transmembrane action potentials and fiinctional refractory periods of canine false tendon and ventricular myocardium: Comparisons in single fibers, Circ Res, 17, pp. 259-273, (1965)
  • [9] Cohen I, Giles W, Noble D, Cellular basis for the T wave of the electrocardiogram, Nature, 262, pp. 657-661, (1976)
  • [10] Gilmour RF, Zipes DP, Different electrophysio‐logical responses of canine endocardium and epicardium to combined hyperkalemia, hypoxia, and acidosis, Circ Res, 46, pp. 814-825, (1980)
12345678910