ELABORATION OF ZIRCONACYCLOPENTANES BY SEQUENTIAL INSERTION OF LITHIUM CHLOROALLYLIDE AND KETONES OR ALDEHYDES

被引：29

作者：

LUKER, T ^{[1
]}

WHITBY, RJ ^{[1
]}

机构：

[1] UNIV SOUTHAMPTON,DEPT CHEM,SOUTHAMPTON SO9 5NH,ENGLAND

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(00)75817-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Insertion of lithium chloropropargylide or lithium chloroallylide into bicycliczirconacyclopentanes gives 1-zirconacyclooct-3-ynes or -3-enes respectively. The former give allenes on protonolysis. The latter react further with ketones or aldehydes to afford 1-zircona-2-oxa-5-decenes which give (E)-homoallyic alcohols on aqueous work-up. With aldehydes moderate 1,6-diastereocontrol is observed.

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页码：785 / 788

页数：4

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