INTRACELLULAR AND EXTRACELLULAR PENETRATION OF AZITHROMYCIN INTO INFLAMMATORY AND NONINFLAMMATORY BLISTER FLUID

被引：28

作者：

FREEMAN, CD

NIGHTINGALE, CH

NICOLAU, DP

BELLIVEAU, PP

BANEVICIUS, MA

QUINTILIANI, R

机构：

[1] HARTFORD HOSP,DEPT PHARM,DIV RES,HARTFORD,CT 06115

[2] HARTFORD HOSP,DEPT MED,DIV INFECT DIS IMMUNOL,HARTFORD,CT 06115

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1994年 / 38卷 / 10期

关键词：

D O I：

10.1128/AAC.38.10.2449

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The penetration of azithromycin into the blister fluids of six volunteers was analyzed after a 5-day regimen (total of 1.5 g). Differences in drug concentrations in a paper disk and serum and in the mass of azithromycin from inflammatory blister chamber leukocytes and noninflammatory blister chamber leukocytes were significant (P < 0.05).

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页码：2449 / 2451

页数：3

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