THYROCALCITONIN - EVIDENCE FOR PHYSIOLOGICAL FUNCTION

被引:95
作者
GRAY, TK
MUNSON, PL
机构
关键词
D O I
10.1126/science.166.3904.512
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A calcium salt given by stomach tube in modest amounts, such as might be ingested in a normal meal, produced hypercalcemia in acutely thyroidectomized fasted rats, whereas in rats with intact thyroid glands the same dose of calcium had little or no detectable effect, presumably because of release of thyrocalcitonin. Thyrocalcitonin apparently protects against hypercalcemia during feeding after deprivation.
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页码:512 / &
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