RAPID DIAGNOSIS OF TICK-BORNE ENCEPHALITIS BY MEANS OF ENZYME LINKED IMMUNOSORBENT ASSAY

被引：64

作者：

HOFMANN, H

FRISCHNIGGEMEYER, W

HEINZ, F

机构：

来源：

JOURNAL OF GENERAL VIROLOGY | 1979年 / 42卷 / MAR期

关键词：

D O I：

10.1099/0022-1317-42-3-505

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

An enzyme-linked immunosorbent assay was applied for determining separately IgM and IgG antibodies against tick-borne encephalitis virus. A micro-modification in microtitre plates proved to be at least as sensitive as the HI test. However, more precise information could be achieved by a macrotest using antigen coated polystyrene balls. False positive results in IgM antibody determinations could be caused by a rheumatoid factor. A high content of IgM antibodies in a serum could impair the determination of its IgG antibodies but not vice versa. Titres were expressed in comparison to a positive control serum.

引用

页码：505 / 511

页数：7

共 19 条

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LEINIKKI, PO
PASSILA, S
[J]. JOURNAL OF INFECTIOUS DISEASES, 1977, 136 : S294 - S299

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