BIOSYNTHESIS OF MALONOMICIN .1. C-13 NUCLEAR MAGNETIC-RESONANCE SPECTRUM AND FEEDING EXPERIMENTS WITH C-13-LABELLED PRECURSORS

被引：20

作者：

SCHIPPER, D ^{[1
]}

VANDERBAAN, JL ^{[1
]}

BICKELHAUPT, F ^{[1
]}

机构：

[1] VRIJE UNIV AMSTERDAM,SCHEIKUNDIG LAB,AMSTERDAM Z,NETHERLANDS

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1979年 / 08期

关键词：

D O I：

10.1039/p19790002017

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 13C n.m.r. spectrum of malonomicin (1) has been completely assigned. The biosynthesis of malonomicin was studied in Streptomyces rimosus by feeding experiments with 13C-labelled precursors. Evidence is presented that malonomicin is derived from 2,3-diaminopropanoic acid, one molecule of acetate, a C4-dicarboxylic acid (presumably succinic acid), CO2, and serine.

引用

页码：2017 / 2022

页数：6

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