PNEUMOCOCCAL VACCINATION OF ELDERLY INDIVIDUALS

被引：11

作者：

FATTALGERMAN, M

TAILLANDIER, J

MATHIEU, D

BIZZINI, B

机构：

[1] INST PASTEUR,DEPT MOLEC TOXICOL,F-75724 PARIS,FRANCE

[2] HOP PAUL BROUSSE,MICROBIOL LAB,F-94800 VILLEJUIF,FRANCE

[3] HOP PAUL BROUSSE,GERIATR UNIT,F-94800 VILLEJUIF,FRANCE

来源：

VACCINE | 1991年 / 9卷 / 08期

关键词：

VACCINATION; PNEUMONIA; ELDERLY; IMMUNOSTIMULATION;

D O I：

10.1016/0264-410X(91)90239-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Pneumococcal infections are still a cause of high morbidity and mortality in elderly populations. Since antibiotics are not wholly effective, vaccination should be performed. The response to pneumococcal vaccination of a limited group of elderly persons aged 60 to 90 years was studied. The sera of most individuals were found to contain antipneumococcal antibodies prior to vaccination. Vaccination resulted in antibody level increases in sera of all subjects except two. On the basis of antibody levels, 19 out of 20 vaccinees proved to be protected after vaccination. Combination of vaccination with a non-specific immunostimulation enhanced the antibody response.

引用

页码：542 / 544

页数：3

共 18 条

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