CONCERNING THE ABSOLUTE STEREOCHEMISTRY OF HONGCONIN

被引：9

作者：

DESHPANDE, PP ^{[1
]}

PRICE, KN ^{[1
]}

BAKER, DC ^{[1
]}

机构：

[1] UNIV TENNESSEE,DEPT CHEM,KNOXVILLE,TN 37996

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1995年 / 5卷 / 10期

关键词：

D O I：

10.1016/0960-894X(95)00165-P

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The heretofore unknown absolute stereochemistry of hongconin has been established to be the 1R, 3R isomer via unambiguous chemical synthesis of its enantiomer. The synthetic scheme allows access to appreciable quantities of enantiopure (-)- or (+)-hongconin, analogues, and related diastereomers.

引用

页码：1059 / 1060

页数：2

共 13 条

[1]

Chen Z, 1981, ZHONGCAOYAO, V12, P484

[2]

CHEN ZX, 1984, HETEROCYCLES, V22, P691

[3]

Ding J, 1982, ZHONGCAOYAO, V13, P499

[4] SYNTHESIS OF FUNCTIONALIZED HYDROXYPHTHALIDES AND THEIR CONVERSION TO 3-CYANO-1(3H)-ISOBENZOFURANONES - THE DIELS-ALDER REACTION OF METHYL 4,4-DIETHOXYBUTYNOATE AND CYCLOHEXADIENES [J].