SYNTHESIS FROM D-GLUCOSE OF ALEXINE [(1R,2R,3R,7S,8S)-3-HYDROXYMETHYL-1,2,7-TRIHYDROXYPYRROLIZIDINE], 3-EPIALEXINE AND 7-EPIALEXINE

被引：44

作者：

FLEET, GWJ ^{[1
]}

HARALDSSON, M ^{[1
]}

NASH, RJ ^{[1
]}

FELLOWS, LE ^{[1
]}

机构：

[1] ROYAL BOT GARDENS,JORDELL LAB,KEW,SURREY,ENGLAND

来源：

TETRAHEDRON LETTERS | 1988年 / 29卷 / 42期

关键词：

D O I：

10.1016/S0040-4039(00)82890-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：5441 / 5444

页数：4

共 9 条

[1] GLYCOSIDASE INHIBITION BY PLANT ALKALOIDS WHICH ARE STRUCTURAL ANALOGS OF MONOSACCHARIDES [J].

EVANS, SV ;

FELLOWS, LE ;

SHING, TKM ;

FLEET, GWJ .

PHYTOCHEMISTRY, 1985, 24 (09) :1953-1955

[2]

FELLOWS LE, 1988, NATURAL PRODUCT ISOL, P540

[3] SYNTHESIS OF DEOXYMANNOJIRIMYCIN FAGOMINE DEOXYNOJIRIMYCIN 2-ACETAMIDO-1,5-IMINO-1,2,5-TRIDEOXY-D-MANNITOL 2-ACETAMIDO-1,5-IMINO-1,2,5-TRIDEOXY-D-GLUCITOL 2S, 3R, 4R, 5R-TRIHYDROXYPIPECOLIC ACID AND 2S, 3R, 4R, 5S-TRIHYDROXYPIPECOLIC ACID FROM METHYL 3-O-BENZYL-2,6-DIDEOXY-2,6-IMINO-ALPHA-D-MANNOFURANOSIDE [J].

FLEET, GWJ ;

FELLOWS, LE ;

SMITH, PW .

TETRAHEDRON, 1987, 43 (05) :979-990

[4] ENANTIOSPECIFIC SYNTHESES OF DEOXYMANNOJIRIMYCIN, FAGOMINE AND 2R,5R-DIHYDROXYMETHYL-3R,4R-DIHYDROXYPYRROLIDINE FROM D-GLUCOSE [J].

FLEET, GWJ ;

SMITH, PW .

TETRAHEDRON LETTERS, 1985, 26 (11) :1469-1472

[5] METHYL 2-AZIDO-3-O-BENZYL-2-DEOXY-ALPHA-D-MANNOFURANOSIDE AS A DIVERGENT INTERMEDIATE FOR THE SYNTHESIS OF POLYHYDROXYLATED PIPERIDINES AND PYRROLIDINES - SYNTHESIS OF 2,5-DIDEOXY-2,5-IMINO-D-MANNITOL [2R,5R-DIHYDROXYMETHYL-3R,4R-DIHYDROXYPYRROLIDINE] [J].

FLEET, GWJ ;

SMITH, PW .

TETRAHEDRON, 1987, 43 (05) :971-978

[6] ISOLATION FROM ALEXA-LEIOPETALA AND X-RAY CRYSTAL-STRUCTURE OF ALEXINE, (1R,2R,3R,7S,8S)-3-HYDROXYMETHYL-1,2,7-TRIHYDROXYPYRROLIZIDINE [(2R,3R,4R,5S,6S)-2-HYDROXYMETHYL-1-AZABICYCLO[3.3.0]OCTAN-3,4,6-TRIOL], A UNIQUE PYRROLIZIDINE ALKALOID [J].

NASH, RJ ;

FELLOWS, LE ;

DRING, JV ;

FLEET, GWJ ;

DEROME, AE ;

HAMOR, TA ;

SCOFIELD, AM ;

WATKIN, DJ .

TETRAHEDRON LETTERS, 1988, 29 (20) :2487-2490

[7]

NASH RJ, 1988, TETRAHEDRON, P44

[8] PYRROLIZIDINE ALKALOIDS [J].

ROBINS, DJ .

NATURAL PRODUCT REPORTS, 1987, 4 (05) :577-590

[9] INHIBITON OF MAMMALIAN DIGESTIVE DISACCHARIDASES BY POLYHYDROXY ALKALOIDS [J].

SCOFIELD, AM ;

FELLOWS, LE ;

NASH, RJ ;

FLEET, GWJ .

LIFE SCIENCES, 1986, 39 (07) :645-650

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