GERM LINE TRANSMISSION AND EXPRESSION OF A CORRECTED HPRT GENE PRODUCED BY GENE TARGETING IN EMBRYONIC STEM-CELLS

被引：339

作者：

THOMPSON, S ^{[1
]}

CLARKE, AR ^{[1
]}

POW, AM ^{[1
]}

HOOPER, ML ^{[1
]}

MELTON, DW ^{[1
]}

机构：

[1] UNIV EDINBURGH, DEPT PATHOL, EDINBURGH EH8 9AG, MIDLOTHIAN, SCOTLAND

来源：

CELL | 1989年 / 56卷 / 02期

关键词：

D O I：

10.1016/0092-8674(89)90905-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：313 / 321

页数：9

共 27 条

[1] FORMATION OF GERM-LINE CHIMERAS FROM EMBRYO-DERIVED TERATOCARCINOMA CELL-LINES
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[J]. NATURE, 1984, 309 (5965) : 255 - 256
[2] TARGETED MUTATION OF THE HPRT GENE IN MOUSE EMBRYONIC STEM-CELLS
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (22) : 8583 - 8587
[3] TARGETED CORRECTION OF A MUTANT HPRT GENE IN MOUSE EMBRYONIC STEM-CELLS
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[J]. NATURE, 1987, 330 (6148) : 576 - 578
[4] ESTABLISHMENT IN CULTURE OF PLURIPOTENTIAL CELLS FROM MOUSE EMBRYOS
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[5] A TECHNIQUE FOR RADIOLABELING DNA RESTRICTION ENDONUCLEASE FRAGMENTS TO HIGH SPECIFIC ACTIVITY
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[J]. ANALYTICAL BIOCHEMISTRY, 1983, 132 (01) : 6 - 13
[6] BEHAVIORAL AND NEUROCHEMICAL EVALUATION OF A TRANSGENIC MOUSE MODEL OF LESCH-NYHAN SYNDROME
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[J]. JOURNAL OF THE NEUROLOGICAL SCIENCES, 1988, 86 (2-3) : 203 - 213
[7] NEW TECHNIQUE FOR ASSAY OF INFECTIVITY OF HUMAN ADENOVIRUS 5 DNA
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[J]. VIROLOGY, 1973, 52 (02) : 456 - 467
[8] HPRT-DEFICIENT (LESCH-NYHAN) MOUSE EMBRYOS DERIVED FROM GERMLINE COLONIZATION BY CULTURED-CELLS
HOOPER, M
HARDY, K
HANDYSIDE, A
HUNTER, S
MONK, M
[J]. NATURE, 1987, 326 (6110) : 292 - 295
[9] METABOLIC COOPERATION BETWEEN MAMMALIAN-CELLS IN CULTURE
HOOPER, ML
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1982, 651 (2-3) : 85 - 103
[10] CHARACTERIZATION, EVOLUTIONARY RELATIONSHIPS, AND CHROMOSOME LOCATION OF PROCESSED MOUSE HPRT-PSEUDOGENE
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MACLEOD, KF
KING, A
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MELTON, DW
[J]. SOMATIC CELL AND MOLECULAR GENETICS, 1988, 14 (04) : 359 - 369

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