INSULIN IMMUNOREACTIVITY IN THE FETAL AND NEONATAL RAT RETINA

被引：13

作者：

MEIMARIDIS, DG

MORSE, DE

PANSKY, B

BUDD, GC

机构：

[1] MED COLL OHIO,DEPT ANAT,TOLEDO,OH 43699

[2] MED COLL OHIO,DEPT PHYSIOL,TOLEDO,OH 43699

来源：

NEUROSCIENCE LETTERS | 1990年 / 118卷 / 01期

关键词：

Developing retina; Immunocytochemistry; Insulin; Rat;

D O I：

10.1016/0304-3940(90)90262-8

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The ganglion cell layer of pre- and postnatal rat retina is positive for insulin immunoreactivity. At birth the inner nuclear layer also stains for insulin. By 5 days after birth the layers characteristic of the mature retina are demonstrable. At this time the outer nuclear layer and both limiting membranes show insulin reactivity. The lens is positive for insulin at all stages studied and the retinal pigment and choroid layers are positive after birth. These observations suggest that insulin may be important in differentiation and/or maturation of the retina. © 1990.

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页码：116 / 119

页数：4

相关论文

共 21 条

[1] ONTOGENY OF CEPHALIC INSULIN RELEASE BY THE RAT [J].

BERNSTEIN, IL ;

WOODS, SC .

PHYSIOLOGY & BEHAVIOR, 1980, 24 (03) :529-532

[2] DETECTION OF INSULIN SYNTHESIS IN MAMMALIAN ANTERIOR-PITUITARY-CELLS BY IMMUNOHISTOCHEMISTRY AND DEMONSTRATION OF INSULIN-RELATED TRANSCRIPTS BY INSITU RNA-DNA HYBRIDIZATION [J].

BUDD, GC ;

PANSKY, B ;

CORDELL, B .

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1986, 34 (05) :673-678

[3]

DAS A, 1987, INVEST OPHTH VIS SCI, V28, P1800

[4] IMMUNOCYTOCHEMISTRY OF MOUSE AND HUMAN RETINA WITH ANTISERA TO INSULIN AND S-100 PROTEIN [J].

DAS, A ;

PANSKY, B ;

BUDD, GC ;

KOLLARITS, CR .

CURRENT EYE RESEARCH, 1984, 3 (12) :1397-1403

[5] INSULIN IS PRESENT IN CHICKEN EGGS AND EARLY CHICK-EMBRYOS [J].

DEPABLO, F ;

ROTH, J ;

HERNANDEZ, E ;

PRUSS, RM .

ENDOCRINOLOGY, 1982, 111 (06) :1909-1916

[6] INSULIN RECOVERABLE FROM TISSUES [J].

ENG, J ;

YALOW, RS .

DIABETES, 1980, 29 (02) :105-109

[7] INSULIN-LIKE IMMUNOREACTIVITY IN CELLS OF THE MOUSE ANTERIOR-PITUITARY [J].

HATFIELD, JS ;

PANSKY, B ;

WALLER, HJ ;

BUDD, GC .

MICRON, 1981, 12 (02) :205-206

[8] IDENTIFICATION OF INSULIN IN RAT-BRAIN [J].

HAVRANKOVA, J ;

SCHMECHEL, D ;

ROTH, J ;

BROWNSTEIN, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (11) :5737-5741

[9]

HENDRICKS SA, 1983, BRAIN PEPTIDES

[10] INSULIN BINDING IN 4 REGIONS OF THE DEVELOPING RAT-BRAIN [J].

KAPPY, M ;

SELLINGER, S ;

RAIZADA, M .

JOURNAL OF NEUROCHEMISTRY, 1984, 42 (01) :198-203