A PNEUMOCOCCAL CLINICAL ISOLATE WITH HIGH-LEVEL RESISTANCE TO CEFOTAXIME AND CEFTRIAXONE

被引：87

作者：

FIGUEIREDO, AMS

CONNOR, JD

SEVERIN, A

PATO, MVV

TOMASZ, A

机构：

[1] ROCKEFELLER UNIV,NEW YORK,NY 10021

[2] UNIV CALIF SAN DIEGO,LA JOLLA,CA 92093

[3] INST NACL SAUDE DR RICARDO JORGE,LISBON,PORTUGAL

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1992年 / 36卷 / 04期

关键词：

D O I：

10.1128/AAC.36.4.886

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A beta-lactam-resistant serotype 23F Streptococcus pneumoniae clinical isolate from the cerebrospinal fluid of a pediatric patient from California is unusual in that the MICs of cefotaxime and ceftriaxone (2.5-mu-g/ml each) are higher than that of benzylpenicillin (0.3-mu-g/ml); the isolate also has patterns of penicillin-binding proteins and of cell wall peptides which are atypical compared with those of previously examined penicillin-resistant pneumococci.

引用

页码：886 / 889

页数：4

共 12 条

[1]

BRADLEY JS, 1991, PEDIATR INFECT DIS J, V10, P871

[2]

FENOLL A, 1990, REV CLIN MICROBIOL, V1, P56

[3]

GARCIABUSTOS J, 1990, P NATL ACAD SCI USA, V87, P5414

[4] PENICILLIN-BINDING PROTEIN FAMILIES - EVIDENCE FOR THE CLONAL NATURE OF PENICILLIN RESISTANCE IN CLINICAL ISOLATES OF PNEUMOCOCCI [J].