ADDITION OF ORGANOLITHIUM COMPOUNDS TO N-THP PROTECTED NITRONE

被引：14

作者：

BASHA, A

RATAJCZYK, JD

BROOKS, DW

机构：

[1] Abbott Laboratories, Abbott Park, IL 60064-3500

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 31期

关键词：

D O I：

10.1016/S0040-4039(00)79375-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel synthesis of a-branched primary hydroxylamines by addition of organolithium reagents to N-THP protected nitrone is described.

引用

页码：3783 / 3786

页数：4

共 17 条

[1] DIASTEREOSELECTIVITY IN THE REACTION OF N-GLYCOSYL-NITRONES - 1,3-DIPOLAR CYCLO-ADDITION AND ADDITION OF PHOSPHITE ANION [J].

BERNET, B ;

KRAWCZYK, E ;

VASELLA, A .

HELVETICA CHIMICA ACTA, 1985, 68 (08) :2299-2311

[2]

BROOKS DW, 1990, AM CHEM SOC M BOSTON

[3] SELECTIVE REDUCTIONS .16. REACTION OF DISIAMYLBORANE IN TETRAHYDROFURAN WITH SELECTED ORGANIC COMPOUNDS CONTAINING REPRESENTATIVE FUNCTIONAL GROUPS [J].

BROWN, HC ;

BIGLEY, DB ;

ARORA, SK ;

YOON, NM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1970, 92 (24) :7161-&

[4]

CARTER GW, 1989, LEUKOTRIENES PROSTAN, P50

[5] DIASTEREOSELECTIVITY OF ORGANOMETALLIC ADDITIONS TO NITRONES BEARING STEREOGENIC N-SUBSTITUENTS [J].

CHANG, ZY ;

COATES, RM .

JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (11) :3464-3474

[6] ASYMMETRIC INDUCTION IN THE ADDITION OF GRIGNARD-REAGENTS TO NITRONES [J].

COWLING, MP ;

JENKINS, PR ;

COOPER, K .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1988, (22) :1503-1504

[7]

FENER H, 1969, J ORG CHEM, V34, P1817

[8]

GRIBBLE GW, 1977, SYNTHESIS-STUTTGART, P856

[9]

HERSCHEID JDM, 1978, TETRAHEDRON LETT, P5143

[10] NUCLEOPHILIC ADDITIONS TO N-GLYCOSYLNITRONES - ASYMMETRIC-SYNTHESIS OF ALPHA-AMINOPHOSPHONIC ACIDS [J].

HUBER, R ;

KNIERZINGER, A ;

OBRECHT, JP ;

VASELLA, A .

HELVETICA CHIMICA ACTA, 1985, 68 (06) :1730-1747

← 1 2 →