IMMUNE EFFECTOR MECHANISMS IN HEART-TRANSPLANT REJECTION

被引：12

作者：

BINAH, O ^{[1
]}

机构：

[1] STANFORD SCH MED,FALK CARDIOVASC RES CTR,DEPT CARDIOVASC MED,STANFORD,CA

来源：

CARDIOVASCULAR RESEARCH | 1994年 / 28卷 / 12期

关键词：

HEART TRANSPLANT REJECTION; MYOCARDITIS AND CARDIOMYOPATHY; CYTOTOXIC T LYMPHOCYTES; VENTRICULAR MYOCYTES; LYTIC GRANULES; PERFORIN;

D O I：

10.1093/cvr/28.12.1748

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

It is well established that immunological mechanisms are responsible for the pathophysiology of several heart diseases, some contributing significantly to morbidity and mortality worldwide. Of the multiple cellular and humoral components participating in the overall immune response in heart diseases, this article mainly deals with cellular immunity mediated by cytotoxic T lymphocytes (CTL). Three important heart diseases have been associated with CTL induced myocardial damage: (1) heart transplant rejection; (2) myocarditis and dilated cardiomyopathy; (3) Chagas heart disease.

引用

页码：1748 / 1757

页数：10

共 131 条

[1] ADAMS PW, 1992, J IMMUNOL, V148, P3753
[2] MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I AND CLASS-II EXPRESSION BY MYOCYTES IN CARDIAC BIOPSIES POSTTRANSPLANTATION
AHMEDANSARI, A
TADROS, TS
KNOPF, WD
MURPHY, DA
HERTZLER, G
FEIGHAN, J
LEATHERBURY, A
SELL, KW
[J]. TRANSPLANTATION, 1988, 45 (05) : 972 - 978
[3] Auchincloss Hugh Jr., 1993, P1099
[4] HEART-TRANSPLANTATION AFTER 16 YEARS
AUSTEN, WG
COSIMI, AB
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1984, 311 (22) : 1436 - 1438
[5] PHENOTYPIC AND FUNCTIONAL-CHARACTERIZATION OF LYMPHOCYTES THAT BIND HUMAN MICROVASCULAR ENDOTHELIAL-CELLS INVITRO - EVIDENCE FOR PREFERENTIAL BINDING OF NATURAL-KILLER-CELLS
BENDER, JR
PARDI, R
KARASEK, MA
ENGLEMAN, EG
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1987, 79 (06) : 1679 - 1688
[6] T-CELL RECEPTOR-NEGATIVE NATURAL-KILLER-CELLS DISPLAY ANTIGEN-SPECIFIC CYTOTOXICITY FOR MICROVASCULAR ENDOTHELIAL-CELLS
BENDER, JR
PARDI, R
ENGLEMAN, E
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (18) : 6949 - 6953
[7] Berke G, 1980, Prog Allergy, V27, P69
[8] BERKE G, 1988, J IMMUNOL, V141, P1429
[9] Berke Gideon, 1993, P965
[10] BEVAN MJ, 1976, J EXP MED, V343, P1283

← 1 2 3 4 5 6 7 8 9 10 →