A NEW OPTIMAL WAVELENGTH FOR TREATMENT OF PORT-WINE STAINS

被引:44
作者
KIENLE, A
HIBST, R
机构
[1] Inst. fur Lasertechnol. in der Medizin und Mestechnik, Ulm
关键词
D O I
10.1088/0031-9155/40/10/001
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In this study we investigate light penetration into skin in order to define the optimal wavelength for the treatment of port wine stains. A two-layer model (epidermis and dermis) is applied with a cylindric tube representing the ectatic blood vessel. Light propagation is calculated by the Monte Carlo method. Values for the optical properties of the skin were not only taken from the literature, but also derived from measurements of the spatially resolved reflectance on the human forearm applying a multilayer model. Using the new values, the maximal depth of selective vascular injury better fits experimental and clinical observations, compared to the values in literature. In addition, the optimal wavelength for treatment of port wine stains is shifted to longer wavelengths.
引用
收藏
页码:1559 / 1576
页数:18
相关论文
共 26 条
[1]  
Anderson R R, 1981, Lasers Surg Med, V1, P263
[2]  
Anderson R. R., 1982, SCI PHOTOMEDICINE, P147, DOI DOI 10.1007/978-1-4684-8312-3_6
[3]   NATURE AND EVOLUTION OF PORT WINE STAINS - COMPUTER-ASSISTED STUDY [J].
BARSKY, SH ;
ROSEN, S ;
GEER, DE ;
NOE, JM .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1980, 74 (03) :154-157
[4]   A REVIEW OF THE OPTICAL-PROPERTIES OF BIOLOGICAL TISSUES [J].
CHEONG, WF ;
PRAHL, SA ;
WELCH, AJ .
IEEE JOURNAL OF QUANTUM ELECTRONICS, 1990, 26 (12) :2166-2185
[5]   A DIFFUSION-THEORY MODEL OF SPATIALLY RESOLVED, STEADY-STATE DIFFUSE REFLECTANCE FOR THE NONINVASIVE DETERMINATION OF TISSUE OPTICAL-PROPERTIES INVIVO [J].
FARRELL, TJ ;
PATTERSON, MS ;
WILSON, B .
MEDICAL PHYSICS, 1992, 19 (04) :879-888
[6]   EFFECT OF DYE-LASER PULSE DURATION ON SELECTIVE CUTANEOUS VASCULAR INJURY [J].
GARDEN, JM ;
TAN, OT ;
KERSCHMANN, R ;
BOLL, J ;
FURUMOTO, H ;
ANDERSON, RR ;
PARRISH, JA .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1986, 87 (05) :653-657
[7]   OPTICAL-PROPERTIES OF HUMAN DERMIS INVITRO AND INVIVO [J].
GRAAFF, R ;
DASSEL, ACM ;
KOELINK, MH ;
DEMUL, FFM ;
AARNOUDSE, JG ;
ZIJLSTRA, WG .
APPLIED OPTICS, 1993, 32 (04) :435-447
[8]   CLINICAL AND HISTOLOGICAL-EVALUATION OF PORTWINE STAIN TREATMENT WITH A MICROSECOND-PULSED DYE-LASER AT 577 NM [J].
HENNING, JPH ;
VANGEMERT, MJC ;
LAHAYE, CTW .
LASERS IN SURGERY AND MEDICINE, 1984, 4 (04) :375-380
[9]  
Ishimaru A., 1987, WAVE PROPAGATION SCA
[10]  
Jacques S. L., 1987, Lasers in the Life Sciences, V1, P309