KETOGENESIS IN VITRO

被引:43
作者
MCGARRY, JD
FOSTER, DW
机构
[1] Department of Internal Medicine, Tho University, Texas Southwestern Medical School, Dallas
关键词
D O I
10.1016/0304-4165(69)90061-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Starvation for 48 h and diabetes (induced either by alloxan treatment or by pancreatectomy) resulted in increasing degrees of ketosis in rats. Optimal conditions were established for acetoacetate synthesis from CoASAc in homogenates of liver taken from animals of all experimental groups. The results obtained from these studies show that the dramatic increase in ketosis associated with starvation and diabetes cannot be accounted for by the minor fluctuations observed in the levels of hepatic enzymes responsible for ketogenesis. © 1969.
引用
收藏
页码:35 / +
页数:1
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