CONSUMPTION OF O-2 AND EARLY DETECTION OF FA-FA GENOTYPE IN RATS

被引：71

作者：

KAPLAN, ML

机构：

[1] Department of Nutrition, Cook College, Rutgers University, New Brunswick, NJ

来源：

METABOLISM-CLINICAL AND EXPERIMENTAL | 1979年 / 28卷 / 11期

关键词：

D O I：

10.1016/0026-0495(79)90154-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Oxygen consumption was determined in 10-12-wk-old fa fa and non-fa fa rats at ambient temperatures of 10°-40°C. The fa fa rats exhibited a lower oxygen consumption than non-fa fa rats from 10°-30°C, but not at 35°C and 40°C. A lower oxygen consumption was also observed among fa fa rats as early as 18 days of age, prior to the phenotypic expression of apparent obesity. Fourteen hundred μliter O2 consumed/hr/g body weight at STP was used as a value, below which future obese rats could be identified among 18-day-old pups from fa/+ × fa/+ crosses. Only a 10% error was found in the use of this value for the early identification of the fa fa genotype. © 1979.

引用

页码：1147 / 1151

页数：5

共 16 条

[1] BELL GE, 1977, GROWTH, V41, P63
[2] OXYGEN CONSUMPTION OF GENETICALLY OBESE RATS
BRAY, GA
[J]. EXPERIENTIA, 1969, 25 (10): : 1100 - &
[3] BRAY GA, 1970, J LIPID RES, V11, P517
[4] OXYGEN-CONSUMPTION RATES IN LITTERS OF THIN AND OBESE HYPERGLYCEMIC MICE
FRIED, GH
[J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1973, 225 (01): : 209 - 211
[5] DEVELOPMENTAL-CHANGES IN FATTY (FAFA) RAT - EVIDENCE FOR DEFECTIVE THERMOGENESIS PRECEDING HYPER-LIPOGENESIS AND HYPERINSULINEMIA
GODBOLE, V
YORK, DA
BLOXHAM, DP
[J]. DIABETOLOGIA, 1978, 15 (01) : 41 - 44
[6] JOHNSON PR, 1971, J LIPID RES, V12, P706
[7] KAPLAN ML, 1973, P SOC EXP BIOL MED, V143, P925, DOI 10.3181/00379727-143-37442
[8] CORE TEMPERATURE, O2 CONSUMPTION, AND EARLY DETECTION OF OB-OB GENOTYPE IN MICE
KAPLAN, ML
LEVEILLE, GA
[J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1974, 227 (04): : 912 - 915
[9] KAPLAN ML, 1977, FED PROC, V36, P1149
[10] KLIMISTAVANTZIS D, 1978, FED PROC, V37, P676

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