Structure of the leucine zipper

被引：269

作者：

Alber, Tom ^{[1
,2
]}

机构：

[1] Univ Utah, Dept Biochem, Sch Med, Salt Lake City, UT 84132 USA

[2] Univ Utah, Dept Chem, Salt Lake City, UT 84132 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1992年 / 2卷 / 02期

关键词：

D O I：

10.1016/S0959-437X(05)80275-8

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In the basic-region leucine-zipper domain, flexible DNA-binding arms are juxtaposed by a two-stranded, parallel coiled-coil motif called the leucine zipper. Genetic, physical and structural studies of the leucine zipper identify interactions that help determine the stability and specificity of dimerization and DNA binding.

引用

页码：205 / 210

页数：6

共 47 条

[1] COGNATE DNA-BINDING SPECIFICITY RETAINED AFTER LEUCINE ZIPPER EXCHANGE BETWEEN GCN4 AND C/EBP [J].

AGRE, P ;

JOHNSON, PF ;

MCKNIGHT, SL .

SCIENCE, 1989, 246 (4932) :922-926

[2] 2 DISTINCT FORMS OF ACTIVE TRANSCRIPTION FACTOR CREB (CAMP RESPONSE ELEMENT BINDING-PROTEIN) [J].

BERKOWITZ, LA ;

GILMAN, MZ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (14) :5258-5262

[3] MAX - A HELIX-LOOP-HELIX ZIPPER PROTEIN THAT FORMS A SEQUENCE-SPECIFIC DNA-BINDING COMPLEX WITH MYC [J].

BLACKWOOD, EM ;

EISENMAN, RN .

SCIENCE, 1991, 251 (4998) :1211-1217

[4] REGULATED EXPRESSION OF 3 C/EBP ISOFORMS DURING ADIPOSE CONVERSION OF 3T3-L1 CELLS [J].

CAO, ZD ;

UMEK, RM ;

MCKNIGHT, SL .

GENES & DEVELOPMENT, 1991, 5 (09) :1538-1552

[5] ALPHA-HELICAL COILED COILS AND BUNDLES - HOW TO DESIGN AN ALPHA-HELICAL PROTEIN [J].

COHEN, C ;

PARRY, DAD .

PROTEINS-STRUCTURE FUNCTION AND GENETICS, 1990, 7 (01) :1-15

[6]

COHEN DR, 1990, ONCOGENE, V5, P929

[7] STRUCTURAL FEATURES IN THE HEPTAD SUBSTRUCTURE AND LONGER RANGE REPEATS OF 2-STRANDED ALPHA-FIBROUS PROTEINS [J].

CONWAY, JF ;

PARRY, DAD .

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 1990, 12 (05) :328-334

[8] 3-STRANDED ALPHA-FIBROUS PROTEINS - THE HEPTAD REPEAT AND ITS IMPLICATIONS FOR STRUCTURE [J].

CONWAY, JF ;

PARRY, DAD .

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 1991, 13 (01) :14-16

[9] THE PACKING OF ALPHA-HELICES - SIMPLE COILED-COILS [J].

CRICK, FHC .

ACTA CRYSTALLOGRAPHICA, 1953, 6 (8-9) :689-697

[10] MOLECULAR CHARACTERIZATION OF THE GCN4-DNA COMPLEX [J].

GARTENBERG, MR ;

AMPE, C ;

STEITZ, TA ;

CROTHERS, DM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (16) :6034-6038

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