HEPATOTOXICITY CAUSED BY THE COMBINED ACTION OF ISONIAZID AND RIFAMPICIN

被引：31

作者：

ASKGAARD, DS ^{[1
]}

WILCKE, T ^{[1
]}

DOSSING, M ^{[1
]}

机构：

[1] BISPEBJERG HOSP,DEPT MED P,DK-2400 COPENHAGEN,DENMARK

来源：

THORAX | 1995年 / 50卷 / 02期

关键词：

TUBERCULOSIS; HEPATOTOXICITY; ISONIAZID; RIFAMPICIN;

D O I：

10.1136/thx.50.2.213

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

A 35 year old black Somalian woman with miliary tuberculosis developed hepatotoxicity after a few days of treatment with isoniazid, rifampicin, pyrazinamide, and ethambutol. After withdrawal of all drugs the liver profile returned to normal and remained so after challenge with isoniazid. Hepatotoxicity recurred when rifampicin was added, but it was well tolerated when reintroduced without isoniazid.

引用

页码：213 / 214

页数：2