INCREASING COMPLEXITY OF THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX

被引：177

作者：

TINSLEY, JM

BLAKE, DJ

ZUELLIG, R

DAVIES, KE

机构：

[1] Molecular Genetics Group, Institute of Molecular Medicine, John Radcliffe Hospital, Headington

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1994年 / 91卷 / 18期

关键词：

D O I：

10.1073/pnas.91.18.8307

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Duchenne muscular dystrophy is a severe X chromosome-linked, muscle-wasting disease caused by lack of the protein dystrophin. The exact function of dystrophin remains to be determined. However, analysis of its interaction with a large oligomeric protein complex at the sarcolemma and the identification of a structurally related protein, utrophin, is leading to the characterization of candidate genes for other neuromuscular disorders.

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页码：8307 / 8313

页数：7

相关论文

共 61 条

[1] 2 FORMS OF MOUSE SYNTROPHIN, A 58-KD DYSTROPHIN-ASSOCIATED PROTEIN, DIFFER IN PRIMARY STRUCTURE AND TISSUE DISTRIBUTION [J].

ADAMS, ME ;

BUTLER, MH ;

DWYER, TM ;

PETERS, MF ;

MURNANE, AA ;

FROEHNER, SC .

NEURON, 1993, 11 (03) :531-540

[2] CLONING OF HUMAN BASIC A1, A DISTINCT 59-KDA DYSTROPHIN-ASSOCIATED PROTEIN ENCODED ON CHROMOSOME 8Q23-24 [J].

AHN, AH ;

YOSHIDA, M ;

ANDERSON, MS ;

FEENER, CA ;

SELIG, S ;

HAGIWARA, Y ;

OZAWA, E ;

KUNKEL, LM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (10) :4446-4450

[3] THE STRUCTURAL AND FUNCTIONAL DIVERSITY OF DYSTROPHIN [J].

AHN, AH ;

KUNKEL, LM .

NATURE GENETICS, 1993, 3 (04) :283-291

[4] LAMININ IN ANIMAL-MODELS FOR MUSCULAR-DYSTROPHY - DEFECT OF LAMININ-M IN SKELETAL AND CARDIAC MUSCLES AND PERIPHERAL-NERVE OF THE HOMOZYGOUS DYSTROPHIC DY/DY MICE [J].

ARAHATA, K ;

HAYASHI, YK ;

KOGA, R ;

GOTO, K ;

LEE, JH ;

MIYAGOE, Y ;

ISHII, H ;

TSUKAHARA, T ;

TAKEDA, S ;

WOO, M ;

NONAKA, I ;

MATSUZAKI, T ;

SUGITA, H .

PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES, 1993, 69 (10) :259-264

[5] DYSTROPHIN-ASSOCIATED GLYCOPROTEIN AND DYSTROPHIN COLOCALIZATION AT SARCOLEMMA IN FUKUYAMA CONGENITAL MUSCULAR-DYSTROPHY [J].

ARAHATA, K ;

HAYASHI, YK ;

MIZUNO, Y ;

YOSHIDA, M ;

OZAWA, E .

LANCET, 1993, 342 (8871) :623-624

[6]

AZIBI K, 1993, HUM MOL GENET, V2, P1423

[7] LINKAGE OF TUNISIAN AUTOSOMAL RECESSIVE DUCHENNE-LIKE MUSCULAR-DYSTROPHY TO THE PERICENTROMERIC REGION OF CHROMOSOME 13Q [J].

BENOTHMANE, K ;

BENHAMIDA, M ;

PERICAKVANCE, MA ;

BENHAMIDA, C ;

BLEL, S ;

CARTER, SC ;

BOWCOCK, AM ;

PETRUKHIN, K ;

GILLIAM, TC ;

ROSES, AD ;

HENTATI, F ;

VANCE, JM .

NATURE GENETICS, 1992, 2 (04) :315-317

[8]

BEWICK GS, 1993, NEUROMUSCULAR DISORD, V3, P503, DOI 10.1016/0960-8966(93)90105-S

[9] DIFFERENT DISTRIBUTIONS OF DYSTROPHIN AND RELATED PROTEINS AT NERVE MUSCLE JUNCTIONS [J].

BEWICK, GS ;

NICHOLSON, LVB ;

YOUNG, C ;

ODONNELL, E ;

SLATER, CR .

NEUROREPORT, 1992, 3 (10) :857-860

[10]

Blake Derek J., 1994, Trends in Cell Biology, V4, P19, DOI 10.1016/0962-8924(94)90034-5

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