INTRANIGRAL INJECTED IRON PROGRESSIVELY REDUCES STRIATAL DOPAMINE METABOLISM

被引：35

作者：

WESEMANN, W ^{[1
]}

BLASCHKE, S ^{[1
]}

SOLBACH, M ^{[1
]}

GROTE, C ^{[1
]}

CLEMENT, HW ^{[1
]}

RIEDERER, P ^{[1
]}

机构：

[1] UNIV WURZBURG,HOSP PSYCHIAT,DEPT NEUROCHEM,WURZBURG,GERMANY

来源：

JOURNAL OF NEURAL TRANSMISSION-PARKINSONS DISEASE AND DEMENTIA SECTION | 1994年 / 8卷 / 03期

关键词：

DOPAMINE METABOLISM; IRON; PULSE VOLTAMMETRY; NEURODEGENERATION; RAT;

D O I：

10.1007/BF02260941

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The striatal dopamine metabolism of the rat was followed 1, 3, and 6 weeks after unilateral intranigral iron (III) (50- and 1.5 mu g) application. For both concentrations a progredient decrease of extraneuronal 3.4-dihydroxyphenylacetic acid (DOPA) levels was observed in the ipsilateral striatum.

引用

页码：209 / 214

页数：6

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