THEILERIA-PARVA - SIGNIFICANCE OF LEUKOCYTES FOR INFECTING CATTLE

被引：20

作者：

BROWN, CGD ^{[1
]}

CUNNINGHAM, MP ^{[1
]}

JOYNER, LP ^{[1
]}

PURNELL, RE ^{[1
]}

BRANAGAN, D ^{[1
]}

CORRY, GL ^{[1
]}

BAILEY, KP ^{[1
]}

机构：

[1] E AFRICAN VET RES ORG, IMMUNOL RES TICK BORNE CATTLE DIS & TICK CONTROL P, KIKUYU, KENYA

来源：

EXPERIMENTAL PARASITOLOGY | 1978年 / 45卷 / 01期

关键词：

Allogeneic inhibition; Artificial feeding technique; Bos taurus Cattle; East Coast fever; Immunological surveillance; Monozygotic twins; parasitic; Protozoa; Rhipicephalus appendiculatus; Theileria parva; Tick; Transplantation antigens;

D O I：

10.1016/0014-4894(78)90044-9

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Using an artificial feeding technique, infective particles of Theileria parva were harvested in bovine blood in capillary tubes from prefed female Rhipicephalus appendiculatus over a 2-hr period. Inoculations of this blood feed pool invariably resulted in the establishment of patent East Coast fever in autogeneic or syngeneic cattle, i.e., the blood donors or their monozygotic twins, but not in unrelated animals. Mechanical passage of 4 × 106 macroschizont-infected lymphoid cells, harvested from a heifer with East Coast fever, successfully induced patent theileriosis in the donor's monozygotic twin but not in a susceptible allogeneic bovid. The significance of parasite-cell association and histocompatibility of infected cells is discussed in relation to natural and mechanical transmission of Theileria parva. © 1978.

引用

页码：55 / 64

页数：10

共 24 条

[1]

Bailey K. P., 1960, Bulletin of epizootic diseases of Africa, V8, P33

[2]

BARNETT SF, 1956, 195556 REP E AFR VET, P20

[3]

BROCKLESBY DW, 1965, VET REC, V77, P512

[4]

Broeklesby D. W., 1961, British Veterinary Journal, V117, P529

[5] INFECTION AND TRANSFORMATION OF BOVINE LYMPHOID-CELLS IN-VITRO BY INFECTIVE PARTICLES OF THEILERIA-PARVA [J].

BROWN, CGD ;

STAGG, DA ;

PURNELL, RE ;

KANHAI, GK ;

PAYNE, RC .

NATURE, 1973, 245 (5420) :101-103

[6]

CUNNINGHAM M P, 1973, International Journal for Parasitology, V3, P335, DOI 10.1016/0020-7519(73)90112-4

[7]

Cunningham M.P., 1973, Bulletin Of Epizootic Diseases of Africa, V21, P235

[8]

CUNNINGHAM M P, 1973, International Journal for Parasitology, V3, P583, DOI 10.1016/0020-7519(73)90082-9

[9]

Hellstrom K E, 1965, Wistar Inst Symp Monogr, V3, P79

[10] MODE OF MULTIPLICATION OF THEILERIA IN CULTURES OF BOVINE LYMPHOCYTIC CELLS [J].

HULLIGER, L ;

WILDE, JKH ;

BROWN, CGD ;

TURNER, L .

NATURE, 1964, 203 (494) :728-+

← 1 2 3 →